Postdoctoral Researcher
Post Details
Job Title
Postdoctoral Researcher
Post Number
1004332
Closing Date
17 Oct 2022
Grade
SC6
Starting Salary
£33,050 - £40,750
Hours per week
37
Project Title
Co-transcriptional control mechanisms at Arabidopsis FLC
Months Duration
24
Interview Date
14 Oct 2022

Job Description

Main Purpose of the Job

Postdoctoral Researchers work with limited supervision to carry out individual and collaborative research projects relevant to the overall needs of the research programme.

Key Relationships

Internal: Line manager, group members and, as necessary, other researchers, research support staff and students across the Institute.

External: Zhe Wu SUSTECH China

Main Activities & Responsibilities

Identify, plan, carry out and modify experiments to meet the objectives of the project
Prepare results, reports and manuscripts for publication in leading scientific journals and other relevant media
Disseminate research findings through presentations to various audiences at internal, national and international meetings
Collaborate with colleagues within the Institute in the development of original and world-class research, including contributing to research proposals and grant applications
Liaise with industry and other external stakeholders
Ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements
Contribute to the smooth running of the group, including the effective use of resources, supervision of visitors to the laboratory and assisting with training others, encouraging scientific excellence
Continually strive for excellence, seeking out and acting on feedback and relevant learning and development opportunities
As agreed with the line manager, any other duties commensurate with the nature of the post, for example, contributing to the work of Institute committees

Person Profile

Education & Qualifications

Requirement
Importance
PhD (full award or expected within 6 months) or equivalent in Molecular Biology or similar discipline
Essential

Specialist Knowledge & Skills

Requirement
Importance
Chromatin analysis, RNA PolII genome wide analysis, characterization of non-coding transcripts,
Essential
Knowledge of molecular biology
Essential
Knowledge in chromatin, transcription, and non-coding RNA analysis
Essential

Relevant Experience

Requirement
Importance
Experience working with chromatin, transcription and non-coding RNA analysis
Essential
Proven record in scientific writing
Essential
Experience of oral research presentations
Essential
Experience of supervising, training and mentoring visitors and students
Desirable
Preparing data / information for grant proposals
Desirable

Interpersonal & Communication Skills

Requirement
Importance
Excellent communication skills, both written and oral, including the ability to present complex information with clarity
Essential
Good interpersonal skills, with the ability to work as part of a team
Essential
Demonstrated ability to work independently, using initiative and applying problem solving skills
Essential
Excellent time management and organisational skills
Essential
Ability to collaborate with internal and external stakeholders
Essential
Ability to follow instructions/Standard Operating Procedures
Essential
Promotes and strives for continuous improvement
Essential

Additional Requirements

Requirement
Importance
Promotes equality and values diversity
Essential
Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
Essential
Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute
Essential
Ability to maintain confidentiality and security of information where appropriate
Essential
Willingness to work outside standard working hours when required
Essential
Ability to undertake occasional travel (national and international) related to collaborations and/or seminars
Essential
Attention to detail
Essential

Who We Are

John Innes Centre

The John Innes Centre is an independent, international centre of excellence in plant and microbial genetics, carrying out fundamental and strategic research, to train scientists and making our findings available to society.

Our research makes use of a wide range of disciplines in the biological and chemical sciences including; cell biology, biochemistry, chemistry, genetics and molecular biology.

For more information about working at the John Innes Centre, please click here.

We pride ourselves on being a welcoming and inclusive working environment for all. We have a diverse and multicultural scientific community and thrive on our European and international links, appointing staff from across the world. Any candidate who would like further information on current or anticipated immigration requirements can contact the HR Team on +44 (0)1603 450888 or nbi.recruitment@nbi.ac.uk.

We are proud to hold a prestigious Athena SWAN Gold award, recognising the impact of our work in promoting gender equality in science. We are also a proud member of the Stonewall Diversity Champion’s programme, a founding signatory of the Tecnician Commitment and, as a Disability Confident employer, guarantee to offer an interview to all disabled applicants who meet the essential criteria for the post.

The John Innes Centre is a registered charity (No. 223852), limited by guarantee (registered in England No. 511709).

Department

Cell & Developmental Biology

Development continues throughout the life of the plant. While many linear pathways affecting development have been discovered and are illustrated by elegant genetic studies, the challenge of the future will be for us to understand how these developmental pathways are integrated, both with themselves as well as with environmental signals, to enable a mature plant to grow from a seed.  Guided by evolutionary principles, the Department uses its knowledge of biological processes obtained in laboratory organisms such as Arabidopsis to understand processes in crop plants such as Brassicas and cereals.  To study this interaction of the plant genome with internal developmental networks and the environment, the Department uses a combination of genetic, cell biological, molecular and evolutionary strategies. The insights we are gaining provide both an increasingly detailed knowledge of the proteins involved in diverse regulatory mechanisms and a conceptual framework in which this knowledge can be related and eventually integrated into a molecular description of plant cell function.   The knowledge the department is creating is relevant to agriculture. Genes that control plant stature, form, over-wintering responses and growth are potentially useful for improving crop performance.

Group Details

The Dean group works on gene regulatory mechanisms linking co-transcriptional processing, transcription and chromatin. The post-docs in the lab work closely together to elucidate mechanisms whereby non-coding transcription impacts sense transcriptional output via epigenetic switches. We focus on one particular gene Arabidopsis FLC, but work closely with collaborators to see if our findings are generic across the genome.

Living in Norfolk

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Postdoctoral Researcher
Salary:            £33,050 - £40,750 per annum depending on qualifications and experience.
Contract:        2 years, full time
Location:        John Innes Centre, Norwich, UK.
Closing date: 17th October 2022
Reference:     1004322

An exciting opportunity has arisen for a Postdoctoral Researcher to join the Dean Group at the John Innes Centre, working on cutting-edge science in the field of Cell and Developmental Biology.

About the John Innes Centre:

The John Innes Centre is an independent, international centre of excellence in plant and microbial sciences. We nurture a creative, curiosity-led approach to answering fundamental questions in bioscience, and translate that knowledge into societal benefits. Our strategic vision, Healthy Plants, Healthy People, Healthy Planet, sets out our ambitious long-term goals for the game changing impact of our science globally. 

Our employees enjoy access to state-of-the-art technology and a diverse range of specialist training opportunities, including support for leadership and management. Click here to find out more about working at the John Innes Centre.

About the Dean Group:

The Dean group works on gene regulatory mechanisms linking co-transcriptional processing, transcription, and chromatin.

The lab’s activities currently focus on:

Quantitative variation in FLC expression – This influences whether a plant overwinters before flowering and is through an antisense-linked chromatin mechanism
Epigenetic switching – Plants remember they have experienced winter in a process called vernalization. This is an epigenetic silencing of FLC expression through a cis-based, Polycomb switching mechanism
Natural variation – Arabidopsis thaliana adaptation to different latitudes has involved noncoding polymorphisms within FLC that confer natural variation in flowering and vernalization response

The Postdoctoral Researchers in the lab work closely together to elucidate mechanisms whereby non-coding transcription impacts sense transcriptional output via epigenetic switches. We focus on one particular gene Arabidopsis FLC but work closely with collaborators to see if our findings are generic across the genome.

The role:

The Postdoctoral Researcher will work on elucidating mechanisms whereby non-coding transcription impacts sense transcriptional output via epigenetic switches. The post holder will develop skills in co-transcriptional mechanisms that determine transcriptional outputs in many genomes. They will interact with scientists in the Dean lab, China and at LMB, Cambridge.

The Postdoctoral Researcher will read widely covering literature from many organisms and they will attend conferences and develop important networks for future collaborations.

The ideal candidate:

They will have a PhD in Molecular Biology or in a related discipline with previous experience working with chromatin, transcription, and non-coding RNA analysis. Good communication and organisation skills with the ability to work independently are also required.

Additional information:

We are an equal opportunities employer, actively supporting inclusivity and diversity.  As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. We are proud to hold a prestigious Gold Athena SWAN award in recognition of our inclusive culture, commitment and good practices towards advancing of gender equality. We offer an exciting, stimulating, diverse research environment and actively promote a family friendly workplace. The Institute is also a member of Stonewall’s Diversity Champions programme.

The John Innes Centre is a registered charity (No. 223852) grant-aided by the Biotechnology and Biological Sciences Research Council.