Postdoctoral Researcher
Post Details
Job Title
Postdoctoral Researcher
Post Number
1003615
Closing Date
10 Feb 2019
Grade
SC6
Starting Salary
£31,250 - £38,100
Hours per week
37
Project Title
Enzymes for scalable carbohydrate synthesis
Expected/Ideal Start Date
01 Apr 2019
Months Duration
9
Interview Date
20 Feb 2019

Job Description

Main Purpose of the Job

Postdoctoral Researchers work with limited supervision to carry out individual and collaborative research projects relevant to the enzymatic synthesis of glycans, sugar nucleotides and sugar phosphates using chemical and enzymatic approaches.

Key Relationships

Internal: Line manager, group members and, as necessary, other researchers, research support staff and students across the Institute.

External: Collaborators at Keele, Manchester and Iceni Diagnostics

Main Activities & Responsibilities

Percentage
Identify, plan, carry out and modify experiments to meet the objectives of the project
45
Prepare results, reports and manuscripts for publication in leading scientific journals and other relevant media
10
Disseminate research findings though presentations to various audiences at internal, national and international meetings
10
Collaborate with colleagues within the Institute in the development of original and world-class research, including contributing to research proposals and grant applications
10
Liaise with industry and other external stakeholders
5
Ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements
5
Contribute to the smooth running of the group, including the effective use of resources, supervision of visitors to the laboratory and assisting with training others, encouraging scientific excellence
5
Continually strive for excellence, seeking out and acting on feedback and relevant learning and development opportunities
5
As agreed with the line manager, any other duties commensurate with the nature of the post, for example, contributing to the work of Institute committees
5

Person Profile

Education & Qualifications

Requirement
Importance
PhD in Chemistry or related discipline
Essential

Specialist Knowledge & Skills

Requirement
Importance
Synthetic carbohydrate chemistry
Essential
Enzymatic synthesis
Essential

Relevant Experience

Requirement
Importance
Demonstrated ability to perform research and develop novel ideas in carbohydrate chemistry
Essential
Proven record in scientific writing
Essential
Experience of oral research presentations
Essential
Experience of supervising, training and mentoring visitors and students
Desirable
Preparing data / information for grant proposals
Desirable

Interpersonal & Communication Skills

Requirement
Importance
Excellent communication skills, both written and oral, including the ability to present complex information with clarity
Essential
Good interpersonal skills, with the ability to work as part of a team
Essential
Demonstrated ability to work independently, using initiative and applying problem solving skills
Essential
Excellent time management and organisational skills
Essential
Ability to collaborate with internal and external stakeholders
Essential
Ability to follow instructions/Standard Operating Procedures
Essential
Promotes and strives for continuous improvement
Essential

Additional Requirements

Requirement
Importance
Promotes equality and values diversity
Essential
Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
Essential
Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute
Essential
Ability to maintain confidentiality and security of information where appropriate
Essential
Willingness to work outside standard working hours when required
Essential
Ability to undertake occasional travel (national and international) related to collaborations and/or seminars
Essential
Attention to detail
Essential

Who We Are

John Innes Centre

The John Innes Centre is an independent, international centre of excellence in plant science and microbiology, carrying out fundamental and strategic research, to train scientists and making our findings available to society.

Our research makes use of a wide range of disciplines in the biological and chemical sciences including; cell biology, biochemistry, chemistry, genetics and molecular biology.

We pride ourselves on being a welcoming and inclusive working environment for all. We have a diverse and multicultural scientific community and thrive on our European and international links. We are proud to hold a prestigious Athena SWAN Gold award, recognising the impact of our work in promoting gender equality in science. We are also a proud member of the Stonewall Diversity Champion’s programme and, as a Disability Confident employer, guarantee to offer an interview to all disabled applicants who meet the essential criteria for the post.

The John Innes Centre is a registered charity (No. 223852), limited by guarantee (registered in England No. 511709) and is an Equal Opportunities Employer.

Department

Biological Chemistry

The Biological Chemistry Department at the John Innes Centre carries out fundamental research on molecular processes in plants and microbes. With activities ranging from determining DNA topoisomerase structure to mechanism and the generation of novel functional nanostructures from engineered viruses, we employ a multidisciplinary approach that embraces contemporary aspects of enzymology, structural and molecular biology, bionanotechnology, carbohydrate and natural product chemistry. Coupled with state-of-the-art platform technologies for structural, proteomic and chemical genomic analysis, the Department bridges the gap between molecular science and cellular and systems biology. Collectively these studies provide key information with which to manipulate and control molecules, pathways and processes of agronomic, environmental and industrial importance.

Group Details

Rob Field’s research focuses on carbohydrate chemistry and biochemistry. He develops chemical probes and uses gene manipulation to impact carbohydrate biosynthesis and degradation pathways, thereby generating new products.

Rob’s research spans a broad range of organisms including plants, algae, bacteria and viruses. This work has resulted in a number of applications, from designer carbohydrates for functional food studies to developing diagnostics for infectious diseases.

. Chemical and enzymatic synthesis
. Small molecule probes
. Glycobiology across a broad range of species
. Carbohydrates play many and varied roles in biology, contributing as energy sources, structural materials, binding and signalling molecules.

In contrast to nucleic acids and proteins, carbohydrates are not template-encoded, which adds enormously to the diversity of carbohydrate structures that may be produced and imparts huge complexity to their analysis and definition of their biological function.

Research in the Field group is focused on developing and exploiting chemical tools and principles to address questions in plant and microbial carbohydrate metabolism. Projects typically involve some combination of chemical and enzymatic synthesis, inhibitor design and assessment, biochemistry, structural biology, metabolomic, proteomic and transcriptomic analysis. From a biology perspective, the lab work cross-Kingdom; Arabidopsis, Barley, Euglena, Streptomyces, E. coli, flu virus, the African and American trypanosome.

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Postdoctoral Researcher

Applications are invited for a Postdoctoral Researcher to join the Laboratory of Rob Field at the John Innes Centre based in Norwich, UK.

Background:

Rob Field’s research focuses on carbohydrate chemistry and biochemistry. He develops chemical probes and uses gene manipulation to impact carbohydrate biosynthesis and degradation pathways, thereby generating new products.

Rob’s research spans a broad range of organisms including plants, algae, bacteria and viruses. This work has resulted in a number of applications, from designer carbohydrates for functional food studies to developing diagnostics for infectious diseases.

The role:

The Postdoctoral Researcher will work with Rob Field's group on the enzymatic synthesis of carbohydrate structures, including oligosaccharides, sugar phosphates and sugar nucleotides. The successful candidate will identify, plan, carry out and modify experiments to meet the objectives of the project.

The ideal candidate:

The ideal candidate will have a PhD in Chemistry or a related discipline. A record of achievement in chemical synthesis, with experience of carbohydrate chemistry, is essential as is experience with the use of enzymes in carbohydrate synthesis. This opportunity would suit a collegiate self-starter who is willing to work in a multidisciplinary project and to deal with collaborators around UK academia and industry.

Additional information:

Salary on appointment will be within the range £31,250 to £38,100 per annum depending on qualifications and experience. This is a full time post, for a contract of 9 months.

Interviews will be held on 20th February 2019.

We are an equal opportunities employer, actively supporting inclusivity and diversity. As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The John Innes Centre is also proud to hold a Gold Award from Athena SWAN and is a member of Stonewall’s Diversity Champions programme.

The closing date for applications will be 10th February 2019.

The John Innes Centre is a registered charity (No. 223852) grant-aided by the Biotechnology and Biological Sciences Research Council and is an Equal Opportunities Employer.