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John Innes Centre
The John Innes Centre is an independent, international centre of excellence in plant science and microbiology, carrying out fundamental and strategic research, to train scientists and making our findings available to society.
Our research makes use of a wide range of disciplines in the biological and chemical sciences including; cell biology, biochemistry, chemistry, genetics and molecular biology.
We pride ourselves on being a welcoming and inclusive working environment for all. We have a diverse and multicultural scientific community and thrive on our European and international links. We are proud to hold a prestigious Athena SWAN Gold award, recognising the impact of our work in promoting gender equality in science. We are also a proud member of the Stonewall Diversity Champion’s programme and, as a Disability Confident employer, guarantee to offer an interview to all disabled applicants who meet the essential criteria for the post.
The John Innes Centre is a registered charity (No. 223852), limited by guarantee (registered in England No. 511709) and is an Equal Opportunities Employer.
- Job Title
- Postdoctoral Researcher
- Post Number
- Closing Date
- 2 Dec 2018
- Starting Salary
- £31,250 - £38,100
- Hours per week
- Project Title
- Dissecting quantitative, analogue, antisense-mediated transcriptional control
- Expected/Ideal Start Date
- 28 Jan 2019
- Months Duration
Main Purpose of the Job
Investigate chromatin switching mechanisms in the quantitative transcriptional regulation of FLC.
Cell & Developmental Biology
The Dean group focuses on co-transcriptional regulation and epigenetic silencing mechanisms in plants.
Applications are invited for a Postdoctoral Scientist to join the Laboratory of Prof. Caroline Dean in the Cell and Developmental Biology department at the John Innes Centre.
The Dean Lab investigates chromatin switching mechanisms that involve co-transcriptional mechanisms and non-coding RNAs. This position is to characterise chromatin switching mechanisms mediating the FCA-regulated quantitative transcriptional regulation of FLC. The post-holder will analyse FLC-Venus expression in a range of fca mutants to investigate how antisense RNA processing establishes particular chromatin states at FLC. They will work independently to identify, plan and carry out experiments to meet the needs of the project. They will also prepare results for publication, attend conferences and contribute to the smooth running of the group.
The ideal candidate:
Candidates are required to have a PhD in molecular biology, with skills in plant molecular biology, as well as experience with RNA analysis and plant-environment interactions. Excellent communication and interpersonal skills are essential.
Salary on appointment will be within the range £31,250 to £38,100 per annum depending on qualifications and experience. This is a full-time post for a contract of 18 months in the first instance.
We are an equal opportunities employer, actively supporting inclusivity and diversity. As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The John Innes Centre is also proud to hold a Gold Award from Athena SWAN and is a member of Stonewall’s Diversity Champions programme.
The post-holder will report directly to Caroline Dean and Martin Howard but will interact on a daily basis with a modeller from the Howard group as well as several other postdocs in the Dean lab
Main Activities & Responsibilities
- Investigate how FCA influences expression of Arabidopsis FLC. They will analyse FLC-Venus expression in a range of genotypes including weak fca alleles.
- Prepare results, reports and manuscripts for publication in leading scientific journals and other relevant media
- Contribute to the smooth running of the group, including the effective use of resources, supervision of visitors to the laboratory and assisting with training others, encouraging scientific excellence
- As agreed with the line manager, any other duties commensurate with the nature of the post.
- Disseminate research findings though presentations to various audiences at internal, national and international meetings
- Ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements
Education & Qualifications
- PhD in molecular biology
Specialist Knowledge & Skills
- Methods for transcriptional analyses in plants
- RNA analysis
- Plant-environment interactions
- Experience in plant molecular biology
Interpersonal & Communication Skills
- Demonstrated passion about their science
- Good interpersonal skills, with the ability to work as part of a team
- Excellent time management and organisational skills
- Excellent communication skills, both written and oral, including the ability to present complex information with clarity
- Ability to follow instructions/Standard Operating Procedures
- Promotes and strives for continuous improvement
- Ability to work independently
- Ability to to use initiative and applying problem solving skills
- Promotes equality and values diversity
- Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
- Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute
- Ability to maintain confidentiality and security of information where appropriate
- Willingness to work outside standard working hours when required
- Ability to undertake occasional travel (national and international) related to collaborations and/or seminars