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John Innes Centre
The John Innes Centre is an independent, international centre of excellence in plant science and microbiology, carrying out fundamental and strategic research, to train scientists and making our findings available to society.
Our research makes use of a wide range of disciplines in the biological and chemical sciences including; cell biology, biochemistry, chemistry, genetics and molecular biology.
We pride ourselves on being a welcoming and inclusive working environment for all. We have a diverse and multicultural scientific community and thrive on our European and international links. We are proud to hold a prestigious Athena SWAN Gold award, recognising the impact of our work in promoting gender equality in science. We are also a proud member of the Stonewall Diversity Champion’s programme and, as a Disability Confident employer, guarantee to offer an interview to all disabled applicants who meet the essential criteria for the post.
The John Innes Centre is a registered charity (No. 223852), limited by guarantee (registered in England No. 511709) and is an Equal Opportunities Employer.
- Job Title
- Research Assistant
- Post Number
- Closing Date
- 19 Jul 2018
- Starting Salary
- £24,300 - £29,750
- Hours per week
- Project Title
- Evolution of Specialized Metabolite Biosynthetic Pathways in the Lamiaceae: Sources of Chemical Diversity for Molecules Essential for Human Use and Plant Defense
- Expected/Ideal Start Date
- 17 Aug 2018
- Months Duration
Main Purpose of the Job
This role is part of a project which explores diversity of terpene-derived metabolites produced by the mint family, and aims to understand how monoterpene and iridoid biosynthesis evolved in this family of plants. The post-holder will perform a range of general tasks including general molecular bioloy and analytical chemistry to support the ongoing research in the lab.
The Biological Chemistry Department at the John Innes Centre carries out fundamental research on molecular processes in plants and microbes. With activities ranging from determining DNA topoisomerase structure to mechanism and the generation of novel functional nanostructures from engineered viruses, we employ a multidisciplinary approach that embraces contemporary aspects of enzymology, structural and molecular biology, bionanotechnology, carbohydrate and natural product chemistry. Coupled with state-of-the-art platform technologies for structural, proteomic and chemical genomic analysis, the Department bridges the gap between molecular science and cellular and systems biology. Collectively these studies provide key information with which to manipulate and control molecules, pathways and processes of agronomic, environmental and industrial importance.
The O'Connor lab is a multidisciplinary laboratory that studies how specialised metabolites are synthesised in plants and microbes. A range of metabolic pathways are under investigation. Group members use molecular biology, protein biochemistry, analytical chemistry, organic chemistry and plant biology to address these problems.
Applications are invited for a Research Assistant to join the Laboratory of Professor Sarah O’Connor at the John Innes Centre.
The John Innes Centre is an independent, international centre of excellence in plant science, genetics and microbiology.
The O'Connor lab is a multidisciplinary laboratory that studies how specialised metabolites are synthesised in plants. A range of metabolic pathways are under investigation. Group members use molecular biology, protein biochemistry, analytical chemistry, organic chemistry and plant biology to address these problems.
This role is part of a project which explores the diversity of terpene-derived metabolites that are produced by the mint family, and to understand how monoterpene and iridoid biosynthesis evolved in this family.
The post-holder will be responsible for receiving shipments of plant material, developing a protocol for extracting metabolites from this plant tissue, developing a mass spectrometry method for analysis, and then analysing these extracts by GC and LC mass spectrometry. The post holder will also need to interpret these mass spectrometry data. The post holder will communicate with the other consortium members to compare and contrast our metabolite data with data acquired by other consortium members.
The post holder will be required to function independently, but will be interacting with a larger group. In addition to working with local group members, this post holder will also participate in periodic project meetings and conference calls with the other project members from the other participating institutions.
The ideal candidate:
To be considered for this role, candidates must possess a BSc in Biology, Chemistry or similar subject. They should have basic molecular biology skills and also data analysis skills. Excellent communication and interpersonal skills are essential.
Salary on appointment will be within the range £24,300 to £29,750 per annum depending on qualifications and experience. This is a full-time post for a contract of 8 months, with possibility of extension.
For further information and details of how to apply, please visit our web site http://jobs.jic.ac.uk or contact the Human Resources team on 01603 450462 or firstname.lastname@example.org quoting reference 1003489.
We are an equal opportunities employer, actively supporting inclusivity and diversity. As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The John Innes Centre is also proud to hold a Gold Award from Athena SWAN and is a member of Stonewall’s Diversity Champions programme.
Work with Line manager, Sarah O'Connor
Interact with O'Connor group members
Interact with other members of this grant consortium at Michigan State, Purdue, and Florida State
Main Activities & Responsibilities
- Help support general lab day-to-day maintenance (help with ordering, freezer organization)
- Perform simple molecular biology
- Purify compounds by HPLC
- Interact with other group members as well as the external consortium members; participate in consortium Skype calls
- Perform LC-MS analysis of plant tissue
- As agreed with line manager, any other duties commensurate with the nature of the role
Education & Qualifications
- BSc, or equivalent, in Biology or Chemistry (or all requirements fulfilled by start of post)
Specialist Knowledge & Skills
- Basic knowledge of chemistry
- Basic molecular biology skills
- Attention to detail
- Ability to interpret mass spectrometry data
- Data analysis skills
- Previous experience of working in a laboratory environment
Interpersonal & Communication Skills
- Excellent communication skills, both written and oral, including the ability to present complex information with clarity
- Excellent time management and organisational skills
- Good interpersonal skills, with the ability to work as part of a team
- Demonstrated ability to work independently, using initiative and applying problem solving skills
- Willingness to work outside standard working hours when required
- Promotes equality and values diversity
- Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it