|John Innes Centre
JIC is an independent, international centre of excellence in plant science and microbiology. Our mission is to carry out fundamental and strategic research, to train scientists and to make our findings available to society.
The scientific research at the Centre makes use of a wide range of disciplines in the biological and chemical sciences, including cell biology, biochemistry, chemistry, genetics and molecular biology.
The John Innes Centre prides itself on being a welcoming and inclusive working environment for all. We have a diverse and multicultural scientific community and thrive on our European and international links. The John Innes Centre is proud to hold a prestigious Athena SWAN Gold award, recognising the impact of our work in promoting gender equality in science. For more information, go to http://www.jic.ac.uk/training-careers/athena-swan/. We are also a proud member of the Stonewall Diversity Champion’s programme and, as a Disability Confident employer, guarantee to offer an interview to all disabled applicants who meet the essential criteria for the post.
The John Innes Centre is a registered charity (No. 223852), limited by guarantee (registered in England No. 511709) and is an Equal Opportunities Employer.
|Job Title||Postdoctoral Researcher (Osbourn Group)|
|Closing Date||7 Feb 2018|
|Starting Salary||£31,250 - £35,400|
|Hours per week
||Triterpene metabolic engineering|
|Expected/Ideal Start Date
||25 Mar 2018|
|Main purpose of the job
||Applications are invited for a Postdoctoral Scientist position in the group of Professor Anne Osbourn at the John Innes Centre to work on engineering of plant natural product pathways using rapid and powerful transient plant expression technology. The successful candidate will join a multidisciplinary team working on discovery, elucidation and reconstitution of pathways for the biosynthesis of medicinally important triterpene glycosides (saponins). |
Further details of this project and the laboratory can be found at https://www.jic.ac.uk/scientists/anne-osbourn/.
||The aims of research in the Department of Metabolic Biology are to understand the basis of diversity in plant metabolism, and the interplay between metabolism and plant nutrition, development and responses to disease and stress. This information underpins the development of sustainable agriculture and bio-based industries.|
||The Postdoctoral Scientist appointed to this position will be based in the Department of Metabolic Biology at the John Innes Centre in the laboratory of Professor Anne Osbourn. The successful candidate will join a multidisciplinary team working on discovery, elucidation and reconstitution of pathways for the biosynthesis of medicinally important triterpene glycosides (saponins). |
Applications are invited for a Postdoctoral Researcher to join the Laboratory of Professor Anne Osbourn at the John Innes Centre.
The successful candidate will join a multidisciplinary team working on discovery, elucidation and reconstitution of pathways for the biosynthesis of medicinally important triterpene glycosides (saponins), and will carry out metabolic engineering using rapid and powerful transient plant expression technology.
This position is part of a package of four postdoctoral positions funded by a Biotechnology and Biological Sciences Research Council (BBSRC) Super Follow-on Fund award for translational research and will provide excellent interdisciplinary training opportunities in plant synthetic biology.
The ideal candidate:
The John Innes Centre is a world-class Institute and is looking to appoint an exceptional candidate with a PhD or equivalent in chemistry, biochemistry, synthetic biology or a related discipline. We will be providing the job-holder with opportunities to develop their technical and transferable skills during this assignment, by way of training programmes, coaching and mentoring.
The successful applicant will have excellent skills in molecular biology, biochemistry and natural product research. Experience of purification and structural analysis of terpenes, and more specifically triterpenes, is desirable. Previous experience of working on glycosylated natural products and on glycosyltransferases would also be advantageous.
Salary on appointment will be within the range £31,250 to £35,400 per annum depending on qualifications and experience. This post is for a contract of two years.
For further information and details of how to apply, please visit our web site http://jobs.jic.ac.uk or contact the Human Resources team on 01603 450462 or firstname.lastname@example.org quoting reference 1003394.
We are an equal opportunities employer, actively supporting inclusivity and diversity. As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The John Innes Centre is also proud to hold a Gold Award from Athena SWAN and is a member of Stonewall’s Diversity Champions programme.
||The successful applicant will be line-managed by Professor Anne Osbourn. The position is part of four postdoctoral positions funded by an Biotechnology and Biological Sciences Research Council (BBSRC) Super Follow-on Fund award for translational research. The successful applicant will work closely with this team and also with JIC Metabolite Services, which has state-of-the art facilities for small molecule analysis. |
|Main Activities & Responsibilities||Percentage|
|Genome mining, vector construction (single and multi-gene), pathway assembly, metabolic engineering||65|
|Collate and analyse results, plan further experiments, discuss with project team||10|
|Presentation of results as papers and seminars, participation in discussion with other collaborators, attending meetings and seminars, outreach||5|
|Contribute to the smooth running of the group, including the effective use of resources, supervision of visitors to the laboratory and assisting with training others, encouraging scientific excellence||5|
|Ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements||5|
|Continually strive for excellence, seeking out and acting on feedback and relevant learning and development opportunities||5|
|As agreed with the line manager, any other duties commensurate with the nature of the post||5||
|Education & Qualifications||Requirement||Importance|
|PhD in natural product chemistry, biochemistry, synthetic biology or a related discipline||Essential||
|Specialist Knowledge & Skills||Requirement||Importance|
|Molecular biology, vector construction||Essential|
|Biochemistry, metabolic biology||Essential|
|Natural products research||Essential|
|Previous experience in molecular biology||Essential|
|Previous experience of natural products research||Essential|
|Previous experience of genome mining using bioinformatics-based approaches||Desirable|
|Previous experience of purification and structural analysis of terpenes||Desirable|
|Previous experience of working on natural product glycoslylation/glycosyltransferases||Desirable||
|Interpersonal & Communication Skills||Requirement||Importance|
|Evidence of intellectual independence, rigour and creativity ||Essential|
|Experience of oral presentation to scientific audiences||Essential|
|Ability to work well in a team||Essential|
|Good verbal and written communication skills||Essential||
|Promotes equality and values diversity||Essential||