|John Innes Centre
JIC is an independent, international centre of excellence in plant science and microbiology. Our mission is to carry out fundamental and strategic research, to train scientists and to make our findings available to society.
The scientific research at the Centre makes use of a wide range of disciplines in the biological and chemical sciences, including cell biology, biochemistry, chemistry, genetics and molecular biology.
The John Innes Centre prides itself on being a welcoming and inclusive working environment for all. We have a diverse and multicultural scientific community and thrive on our European and international links. The John Innes Centre is proud to hold a prestigious Athena SWAN Gold award, recognising the impact of our work in promoting gender equality in science. For more information, go to http://www.jic.ac.uk/training-careers/athena-swan/. We are also a proud member of the Stonewall Diversity Champion’s programme and, as a Disability Confident employer, guarantee to offer an interview to all disabled applicants who meet the essential criteria for the post.
The John Innes Centre is a registered charity (No. 223852), limited by guarantee (registered in England No. 511709) and is an Equal Opportunities Employer.
|Job Title||Postdoctoral Researcher (Osbourn Group)|
|Closing Date||7 Feb 2018|
|Starting Salary||£31,250 - £35,400|
|Hours per week
||Natural product chemist|
|Expected/Ideal Start Date
||25 Mar 2018|
|Main purpose of the job
||Applications are invited for a Postdoctoral Scientist with expertise in natural products chemistry. The post involves extraction, purification and characterisation of medicinally important simple and complex triterpenes generated using synthetic biology-based approaches. The successful candidate will work with other researchers within the Osbourn lab as part of a multi-disciplinary team. |
Further details of this project and the laboratory can be found at https://www.jic.ac.uk/scientists/anne-osbourn/.
||The aims of research in the Department of Metabolic Biology are to understand the basis of diversity in plant metabolism, and the interplay between metabolism and plant nutrition, development and responses to disease and stress. This information underpins the development of sustainable agriculture and bio-based industries.|
||The Postdoctoral Scientist appointed to this position will be based in the Department of Metabolic Biology at the John Innes Centre. |
||Postdoctoral Researcher (Osbourn Group)|
Applications are invited for a Postdoctoral Researcher to join the Laboratory of Ann Osbourn at the John Innes Centre (JIC).
The postholder will develop strategies for the extraction, purification and characterisation of medicinally important simple and complex triterpenes (saponins) generated using synthetic biology approaches.
The successful applicant will join a team led by Professor Anne Osbourn at JIC working on metabolic engineering of plant-derived natural products using rapid and powerful transient plant expression technology. The JIC has state-of-the-art facilities for small molecule analysis.
The position is one of four postdoctoral positions funded by a Biotechnology and Biological Sciences Research Council (BBSRC) Super Follow-on Fund award for translational research and will provide excellent interdisciplinary training opportunities in plant synthetic biology.
The ideal candidate:
The John Innes Centre is a world-class Institute and is looking to appoint an exceptional candidate with a PhD or equivalent in chemistry, biochemistry or a related discipline. We will be providing the job-holder with opportunities to develop their technical and transferable skills during this assignment, by way of training programmes, coaching and mentoring.
The successful applicant will have excellent natural products chemistry skills, including in extraction, purification and structural elucidation. Experience of GC-MS, LC-MS and NMR are essential. Experience of working with terpenes, and more specifically triterpenes, is desirable.
Salary on appointment will be within the range £31,250 to £35,400 per annum depending on qualifications and experience. This post is for a contract of two years.
For further information and details of how to apply, please visit our web site http://jobs.jic.ac.uk or contact the Human Resources team on 01603 450462 or email@example.com quoting reference 1003389.
We are an equal opportunities employer, actively supporting inclusivity and diversity. As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The John Innes Centre is also proud to hold a Gold Award from Athena SWAN and is a member of Stonewall’s Diversity Champions programme.
||The successful applicant will be line-managed by Professor Anne Osbourn. The position is one of four postdoctoral positions funded by a Biotechnology and Biological Sciences Research Council (BBSRC) Super Follow-on Fund award for translational research. The successful applicant will work closely with this team and with John Innes Centre Metabolite Services. |
|Main Activities & Responsibilities||Percentage|
|Extraction, purification and characterisation of simple and complex triterpenes (saponins)||65|
|Collate and analyse results, plan further experiments, discuss with project team||10|
|Presentation of results as papers and seminars, participation in discussion with other collaborators, attending meetings and seminars, outreach||5|
|Contribute to the smooth running of the group, including the effective use of resources, supervision of visitors to the laboratory and assisting with training others, encouraging scientific excellence ||5|
|Ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements||5|
|Continually strive for excellence, seeking out and acting on feedback and relevant learning and development opportunities||5|
|As agreed with the line manager, any other duties commensurate with the nature of the post||5||
|Education & Qualifications||Requirement||Importance|
|PhD in chemistry, biochemistry or a related discipline, or equivalent||Essential||
|Specialist Knowledge & Skills||Requirement||Importance|
|Knowledge of GC-MS and/or LC-MS||Essential|
|Natural product chemistry, including extraction, purification and structural elucidation||Essential|
|Knowledge of NMR, metabolite profiling/metabolomics||Essential||
|Extensive experience in natural product chemistry ||Essential|
|Previous experience of compound extraction, purification and characterisation||Essential|
|Experience of GC-MS and/or LC-MS; NMR, metabolic profiling/metabolomics||Essential|
|Experience of analysing terpenes||Desirable||
|Interpersonal & Communication Skills||Requirement||Importance|
|Evidence of intellectual independence, rigour and creativity ||Essential|
|Experience of oral presentation to scientific audiences||Essential|
|Ability to work well in a team||Essential|
|Good verbal and written communication skills||Essential||
|Promotes equality and values diversity||Essential|
|Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute ||Essential|
|Willingness to work outside standard working hours when required ||Essential||